Advances in ataxia research to be featured at USF's Innovative Learning and Simulation Center

Public release date: 28-Aug-2012
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Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3303
University of South Florida (USF Health)

Friedreich's Ataxia Research Alliance and University of South Florida host Sept. 6 live streamed event

Tampa, FL (Aug. 27, 2012) Scientists, clinicians and patients will gather at the University of South Florida's Center for Advanced Medical Learning and Simulation (CAMLS) in downtown Tampa Sept. 6 to share research insights and energize the search for a cure for Friedreich's ataxia and related disorders.

The fourth annual scientific symposium "Understanding a Cure" will be held from 6 to 8 p.m. on Thursday, Sept. 6, at USF Health CAMLS, 124 South Franklin Street, Tampa, FL 33602. The symposium, free and open to the public, is hosted by Friedreich Ataxia Research Alliance (FARA) and the USF Ataxia Research Center (ARC), and will include a tour of CAMLS.

This year, for the first time, the scientific symposium will be live streamed through the FARA Facebook page, with opportunities for visitors to join the discussion long distance. To connect to the live stream and learn about cutting edge research advances in Friedreich's ataxia, visit: http://www.facebook.com/CureFA/app_196506863720166 on September 6 at 6 p.m. A Facebook account is not needed to join.

Friedreich's ataxia is a rare, debilitating neuromuscular disorder. Symptoms, typically emerging between ages 5 and 15, often progress to severe disability and include the following: loss of coordination and muscle weakness that leads to wheelchair use, energy deprivation and fatigue, vision impairment, hearing loss, slurred speech, aggressive scoliosis, diabetes, and life-shortening cardiac disease. There is not yet an approved treatment or a cure.

"This year's Friedreich's Ataxia Symposium will build upon the momentum of the last three years by highlighting some of the most promising discoveries yet from leading researchers in the field," said Theresa Zesiewicz, MD, professor of neurology and director of the University of South Florida Ataxia Research Center, who moderates the symposium. "The opportunity for patients who cannot be with us in person to join the interactive symposium in real-time via Facebook has generated a lot of excitement. We're looking forward to lively discussions."

Symposium speakers will include Helene Puccio, PhD, research director for INSERM, Department of Translational Medicine and Neurogenetics, Institute of Genetics and Molecular and Cellular Biology (IMCBG) in Illkirch, France. Dr. Puccio's laboratory develops animal and cell models to help understand the pathophysiology of Friedreich's ataxia and the function of frataxin, a protein severely deficient in people with Friedreich's ataxia. The preclinical models are used by Puccio and other researchers worldwide searching for potential new treatment approaches to ataxias, including gene replacement therapy.

Pediatric cardiologist R. Mark Payne, MD, professor of pediatrics and medical and molecular genetics director at Wells Center for Pediatric Research-Indiana University School of Medicine, will share his expertise on cardiomyopathy, or deterioration of heart muscle, related to Friedreich's ataxia. Dr. Payne conducts research on heart disease caused by mitochondrial defects.

Guy Miller, MD, PhD, CEO of Edison Pharmaceuticals, Inc., will speak about advances in developing drugs to treat mitochondrial diseases that share a common feature defects in how the body makes and regulates energy metabolism.

FARA President Ron Bartek and Jennifer Farmer, FARA executive director, will address progress nationwide in the research and management of Friedreich's ataxia.

Stephen Klasko, MD, CEO for USF Health and dean of the Morsani College of Medicine, will moderate a panel discussion on patients' perspectives of living with ataxias.

USF is one of 11 sites included in FARA's Collaborative Clinical Research Network, an international network of centers that share data and resources to advance treatments and clinical research for people with Friedreich's ataxia.

###

For more information about the symposium, please call (813) 974-5909.

- About USF Health

USF Health is dedicated to creating a model of health care based on understanding the full spectrum of health. It includes the University of South Florida's colleges of Medicine, Nursing, Public Health and Pharmacy, the School of Biomedical Sciences and the School of Physical Therapy and Rehabilitation Sciences; and the USF Physician's Group. Ranked 34th in federal research expenditures for public universities by the National Science Foundation, the University of South Florida is a high impact global research university.

- About The Friedreich's Ataxia Research Alliance (FARA) -

FARA is a non-profit organization dedicated to curing FA through research. FARA grants and activities provide support for basic and translational FA research, pharmaceutical/biotech drug development, clinical trials, and scientific conferences. For more information, go to www.curefa.org.

---

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 28-Aug-2012
[ | E-mail | Share ]

Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3303
University of South Florida (USF Health)

Friedreich's Ataxia Research Alliance and University of South Florida host Sept. 6 live streamed event

Tampa, FL (Aug. 27, 2012) Scientists, clinicians and patients will gather at the University of South Florida's Center for Advanced Medical Learning and Simulation (CAMLS) in downtown Tampa Sept. 6 to share research insights and energize the search for a cure for Friedreich's ataxia and related disorders.

The fourth annual scientific symposium "Understanding a Cure" will be held from 6 to 8 p.m. on Thursday, Sept. 6, at USF Health CAMLS, 124 South Franklin Street, Tampa, FL 33602. The symposium, free and open to the public, is hosted by Friedreich Ataxia Research Alliance (FARA) and the USF Ataxia Research Center (ARC), and will include a tour of CAMLS.

This year, for the first time, the scientific symposium will be live streamed through the FARA Facebook page, with opportunities for visitors to join the discussion long distance. To connect to the live stream and learn about cutting edge research advances in Friedreich's ataxia, visit: http://www.facebook.com/CureFA/app_196506863720166 on September 6 at 6 p.m. A Facebook account is not needed to join.

Friedreich's ataxia is a rare, debilitating neuromuscular disorder. Symptoms, typically emerging between ages 5 and 15, often progress to severe disability and include the following: loss of coordination and muscle weakness that leads to wheelchair use, energy deprivation and fatigue, vision impairment, hearing loss, slurred speech, aggressive scoliosis, diabetes, and life-shortening cardiac disease. There is not yet an approved treatment or a cure.

"This year's Friedreich's Ataxia Symposium will build upon the momentum of the last three years by highlighting some of the most promising discoveries yet from leading researchers in the field," said Theresa Zesiewicz, MD, professor of neurology and director of the University of South Florida Ataxia Research Center, who moderates the symposium. "The opportunity for patients who cannot be with us in person to join the interactive symposium in real-time via Facebook has generated a lot of excitement. We're looking forward to lively discussions."

Symposium speakers will include Helene Puccio, PhD, research director for INSERM, Department of Translational Medicine and Neurogenetics, Institute of Genetics and Molecular and Cellular Biology (IMCBG) in Illkirch, France. Dr. Puccio's laboratory develops animal and cell models to help understand the pathophysiology of Friedreich's ataxia and the function of frataxin, a protein severely deficient in people with Friedreich's ataxia. The preclinical models are used by Puccio and other researchers worldwide searching for potential new treatment approaches to ataxias, including gene replacement therapy.

Pediatric cardiologist R. Mark Payne, MD, professor of pediatrics and medical and molecular genetics director at Wells Center for Pediatric Research-Indiana University School of Medicine, will share his expertise on cardiomyopathy, or deterioration of heart muscle, related to Friedreich's ataxia. Dr. Payne conducts research on heart disease caused by mitochondrial defects.

Guy Miller, MD, PhD, CEO of Edison Pharmaceuticals, Inc., will speak about advances in developing drugs to treat mitochondrial diseases that share a common feature defects in how the body makes and regulates energy metabolism.

FARA President Ron Bartek and Jennifer Farmer, FARA executive director, will address progress nationwide in the research and management of Friedreich's ataxia.

Stephen Klasko, MD, CEO for USF Health and dean of the Morsani College of Medicine, will moderate a panel discussion on patients' perspectives of living with ataxias.

USF is one of 11 sites included in FARA's Collaborative Clinical Research Network, an international network of centers that share data and resources to advance treatments and clinical research for people with Friedreich's ataxia.

###

For more information about the symposium, please call (813) 974-5909.

- About USF Health

USF Health is dedicated to creating a model of health care based on understanding the full spectrum of health. It includes the University of South Florida's colleges of Medicine, Nursing, Public Health and Pharmacy, the School of Biomedical Sciences and the School of Physical Therapy and Rehabilitation Sciences; and the USF Physician's Group. Ranked 34th in federal research expenditures for public universities by the National Science Foundation, the University of South Florida is a high impact global research university.

- About The Friedreich's Ataxia Research Alliance (FARA) -

FARA is a non-profit organization dedicated to curing FA through research. FARA grants and activities provide support for basic and translational FA research, pharmaceutical/biotech drug development, clinical trials, and scientific conferences. For more information, go to www.curefa.org.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-08/uosf-aia082712.php

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Samsung verdict could benefit Nokia, shares climb

Shares of Nokia Corp. surged on Monday after a Wall Street analyst said that the Finnish phone maker could benefit from the $1 billion patent verdict against Samsung. The decision could delay technology developments for devices that, like Samsung phones, run Google Inc.'s Android operating system. That could boost Nokia's line of Windows Phone-based smartphones.

THE SPARK: A federal jury in San Jose Friday found that some of Samsung Electronics Co.'s products illegally copied features and designs from Apple Inc.'s iPhone and iPad.

THE BIG PICTURE: Nokia was the world's leading mobile phone maker for more than a decade but was was overtaken by Samsung in the first quarter, according to research firm Gartner. The company has been fighting fierce competition from the iPhone and Android-based smartphones.

As part of its turnaround effort, it has based its new smartphone line on Microsoft Corp.'s Windows Phone operating system, not on the popular Android system. But sales of phones using Windows Phone have been slow.

THE ANALYSIS: The verdict against Samsung could give Nokia an edge. The Windows Phone is substantially different from Apple's iPhone operating system and hasn't landed in its legal sights, and some Wall Street analysts say that the verdict against Samsung is likely to slow growth of smartphones that run on Android.

Phones made by Samsung, HTC, LG and Motorola, now a division of Google, use Android.

In a research note published Monday, Wunderlich Securities analyst Matthew Robison echoed that outlook, saying that the $1 billion verdict and possible punitive damages could slow or postpone Android innovation. And any damage to Android favors Nokia's smartphone business, he wrote.

Robison also assumes that smartphone features that were central in Apple's successful patent claims against Samsung will not be contested by Apple on Windows Phone products, noting that Apple and Microsoft have reached agreements on some patents.

"We believe this implies a significant positive shift in application developer sentiment toward Windows Phone," Robison wrote.

But Nokia may face increased competition from Android phones in markets outside the U.S., where prospects for future patent claims by Apple are more remote, Robison said.

The analyst raised his price target for Nokia to 2.50 euros ($3.13) from 2 euros ($2.50). He kept a "Hold" on the stock.

Nokia did not immediately respond to a message seeking comment.

SHARE ACTION: Nokia's U.S.-traded shares gained 20 cents, or 6.5 percent, to $3.28 in afternoon trading. Shares have lost 36 percent of their value this year.

Source: http://news.yahoo.com/samsung-verdict-could-benefit-nokia-shares-climb-190850405--finance.html

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User:CodieBrogdon339 - wiki@bplsilva

From wiki@bplsilva

These Are Some Of The Tools You Need For Doing Home Improvements

Before you start any home improvement project, you also have to choose the appropriate tools for the project. Sometimes our old tools will do the trick, but more times than not, new tools must be purchased for specific projects. Tools and equipment are necessary to do any type of home improvement project, especially on your own. Here are some proven tips on choosing the right tools for home-improvement undertaking.

Anyone that starts a home improvement project must consider all of the essentials before they begin. Screwdrivers are an essential part of any project like this, especially kits that come with different sizes and styles. Phillips and flat screwdrivers are standard with any kit that you purchase. Anyone that does a project like this should also have a claw hammer at their disposal. Another very useful tool to have is a pair of pliers. These can be used for a variety of reasons and come in different shapes and sizes. Slip joint pliers are probably the most useful all around variety you can get, as these can open to several different widths. If you have siding that you need to take off of the wall, or flooring that needs to be removed, a pry-bar is also a great tool to have.

Lighting is very important when doing jobs around the home. To need to make sure you have some kind of lighting when you are working in a dark space without power, but this shouldn't be an issue when you are working in a home with electricity. A reliable flashlight is a useful tool to have in many situations.

They come in various sizes, and it would be a good idea to have several different ones. For most jobs, you will need the use of your hands, so you will need a light, like the ones miners wear when they work, which is called a hands free headlamp. Anytime there isn't the proper lighting, such as dark stairways, the situation can become dangerous.

For more info construction leads

For many of the home repairs you will be doing, without a ladder you will never reach them. Pretty much any job done on the outside of your house will need a quality ladder, because you will be climbing up on a roof to repair shingles, or do exterior painting. For indoor tasks, you won't need to climb very high, so a stepladder will be all you need. An extension ladder that can be adjusted to different heights will be needed for many jobs. Ladders come with duty ratings, which tell you how much weight they can safely hold. Your needs in this area depend on how much you weigh, and what you may be carrying. Usually when you are climbing up a ladder, you will be carrying something, so figure that weight in also, when you are trying to determine what ladder you need. It is dangerous to have to stretch out to reach something, so make sure you have a ladder that is long enough.

As you can see, different tools and strategies must be used to properly complete your home improvement plan efficiently. Before your project begins, the research should be complete along with gathering the tools you will utilize. Catering to your own personal preferences, and to what you need to complete the job, get power tools (and manually operated ones) before you start. Having the most efficient tools can reduce the amount of time it takes and give you more impressive results.

Source: http://bplsilva.com/wiki/index.php/User%3ACodieBrogdon339

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On the Call: Ford CEO Alan Mulally

Ford Motor Co. reported its 13th consecutive quarterly profit Wednesday and beat Wall Street's earnings and revenue forecasts, prompting Standard and Poor's and others to reiterate their "buy" ratings on Ford shares. But the shares are languishing around $9, less than half their value at the beginning of 2011. On Wednesday, they hit a new 52-week low of $8.92.

That led an analyst to ask CEO Alan Mulally why Ford's shares aren't performing better during a conference call to discuss the company's second-quarter earnings.

QUESTION: "Your stocks sit in the $9 range here, it's a price level we haven't seen since December 2009, which is a year where I think Ford make l$0.01 of earnings per share ... As an industrialist and a business leader, what do you read into that? What do you think the market is missing about Ford here?"

MULALLY: "Well, I think it's in the context of a very tough business environment worldwide. I think people are starting to appreciate that we have a tremendous presence and operation in Europe. We have made money there over the last eight years, but are seeing this very significant deterioration in the economy and the industry. And so I think that's weighing on people's minds.

"I think it's more of the volatility of the world. I think people really do appreciate the value-creation potential going forward, by supporting the customers all around the world. Even during the toughest of times, we continue to restructure our operations to operate profitability at the lower demand, the current demand. And also, we are accelerating the investment in these new products around the world. So I think both the things are in play. I think the best thing we can do for value creation is to continue to implement the Ford plan of delivering a viable, exciting, profitably growing company, and I think that will be appreciated over time."

Source: http://news.yahoo.com/call-ford-ceo-alan-mulally-214326190--finance.html

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Settlement Funding Discussed on CBS - CBC Settlement Funding

In today?s tough economic climate, consumers are trying to stretch their budgets as far as they can. For those of you with structured settlements, getting your hands on financial resources sooner rather than later can help both in the short and long-term.

Recently, James Goodman, managing partner of CBC Settlement Funding, sat down with Erika Von Tiehl of Talk Philly, a CBS affiliate morning talk show, to discuss what financial options consumers have for their structured settlements.

CBC Settlement Funding is an experienced company that can help guide you through the structured settlement process. If you?re interested in getting a lump sum cash payout for your structured settlement or annuity, call CBC at 877-386-3377 today.

Source: http://www.cbcsettlementfunding.com/settlement-funding-on-cbs

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Put Down The Cornerstone Of An Effective Retirement Savings ...

When you start a job, you can easily assume that you are at some point going to retire. Retirement Plans are one of the only ways to get money when your working time is over; however some people do not believe retirement plans are necessary. Of course the first step is planning so that you can form a successful retirement plan. Much like anything in the real world, a structure is only as good as its base.

Time spent on the planning phase is time invested with benefits to be reaped later. Eventually a good plan will mean that analyzing is a thing of the past, but profit is the present and future. So spend quality time planning your retirement plan so that you are happy.

Discussed below are some nuggets of wisdom that can be instrumental as you start your journey of retirement savings. Retirement savings plan can have unexpected turning points, so make sure you read the below tips to be aware of such circumstances.

Make use of your employer sponsored scheme. These plans often have very good benefits that many people do not notice. The best part about choosing a plan like this is that whilst you donate a certain amount into your pension, the employer donates more. More often than not this amount is irrespective of wages and simply looks like free cash.

As mentioned at the investment funds uk website, you should only look to invest in reputable advisory structures. Whilst some may think that there is no need for professional advice, if you are not knowledgeable in the investing world every little bit of advice is going to help. Qualified investment advisors can be found in most financial institutions and offer great information. This information is useful and if harnessed can set the course for a good retirement saving plan.

If you are interested in both short-term and long-term investment plans, an advisor should be able to cater for both. You should use the ISA allowance site or similar, if you have difficulty finding a good investment expert to guide you. An example of such vehicles is structured insurance policies which in addition to taking care of your future can give you short-term benefits. Maximizing your return will also be something to talk about.

Know your risk appetite and invest in a plan that best suits you. Risk tolerance is different in each and every one of us. They are those that are risk averse while others are risk neutral and some risk takers. Before you take any retirement savings plan, know how it is going to fit into your profile and whether you can accommodate it or not. The only advise is to make sure you are comfortable with your investments.

Retirement planning therefore is as important as the funds that will be put in the plan. A mantra goes that ?failing to plan is planning to fail.? It is therefore paramount that the person considering a retirement savings plan thinks not only of the present but also should have a crystallized perspective of the future.

Related posts:

1. Effective Retirement Planning Starts With These 3 Tips
2. Utilize Low Tax Investments To Build Your Retirement Pot
3. Financial Planning Requires Strong Knowledge, Employ a Financial Planner or Financial Adviser
4. Getting Business enterprise Program in the Business
5. We are an unbiased financial advisor in Tyrone, delivering specialist guidance to companies as well as to individuals on their personal finances

Source: http://www.moneyblog.org.uk/2012/07/put-down-the-cornerstone-of-an-effective-retirement-savings-program/

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